Agenerase Drug Interactions

Agenerase drug interactions may occur when the medication is taken with antacids, arrhythmia medications, and certain antibiotics, among other things. These interactions can alter the amount of the medications in your blood, possibly reducing their effectiveness or increasing the risk of side effects. To avoid Agenerase drug interactions, tell your healthcare provider about all medications you are taking.

Agenerase Drug Interactions: An Overview

Agenerase is no longer available in the United States. The manufacturer stopped making it due to low demand, since it has been largely replaced by fosamprenavir (Lexiva®), a similar medication.


Agenerase® (amprenavir) can potentially interact with several other medicines. Some of the medicines that may lead to Agenerase drug interactions include:
  • Alcohol
  • Antacids
  • Arrhythmia medications
  • Certain antibiotics and antifungal medications, such as:
    • Ketoconazole (Nizoral®)
    • Itraconazole (Sporanox®)
    • Rifabutin (Mycobutin®)
    • Rifampin (Rifadin®
  • Certain benzodiazepines, such as:
    • Bromocriptine (Parlodel®)
    • Dihydroergotamine (Migranal®)
    • Ergonovine
    • Ergotamine (Bellamine S®, Cafergot®, Ergomar®)
    • Methylergonovine (Methergine®)
    • Pergolide (Permax®)


  • Phosphodiesterase type 5 inhibitors (PDE5 inhibitors), including:



Agenerase for HIV/AIDS

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