Products That Interfere With Aptivus
Aptivus Interactions Explained
The following sections explain in detail the potentially negative interactions that can occur when Aptivus is combined with any of the drugs listed above.
Aptivus can significantly decrease the level of abacavir in your blood, possibly making it less effective. Your healthcare provider may need to increase your abacavir dosage or recommend a different combination of medications.
Aptivus should not be combined with alfuzosin, as this may increase the amount of alfuzosin in the blood to dangerous levels.
Aptivus can increase the level of many antidepressants in the blood, possibly increasing the risk of side effects. Your healthcare provider may need to decrease the dose of your antidepressant to prevent this interaction from occurring.
Aptivus should never be combined with amiodarone (Cordarone®, Pacerone®), flecainide (Tambocor™), propafenone (Rythmol®), or quinidine, due to the risk of dangerous reactions.
Aptivus may increase the level of bosentan in your blood. Your healthcare provider may need to lower your bosentan dosage while you are taking Aptivus.
Calcium Channel Blockers
Aptivus may affect the level of calcium channel blockers in your blood. Your healthcare provider may need to adjust the dose of your calcium channel blocker to prevent this.
Certain Antibiotics or Antifungals
Combining Aptivus with certain antibiotics or antifungals may increase or decrease the level of both Aptivus and the antibiotic or antifungal in your blood. Check with your healthcare provider before taking Aptivus with any of these medications. It should never be combined with rifampin, since rifampin may make Aptivus less effective.