How Epoetin Alfa Works and What to Tell Your Doctor

Important Information for Your Healthcare Provider

You should talk with your healthcare provider prior to taking epoetin alfa if you have:
Also, let your healthcare provider know if you are:
Make sure to tell your healthcare provider about all other medicines you are taking, including prescription and nonprescription medications, vitamins, and herbal supplements.
(Click Precautions and Warnings With Epoetin Alfa to learn more, including information on who should not take the drug.)

How Does Epoetin Alfa Work?

Epoetin alfa is a manufactured version of erythropoietin, a human protein that is produced in the kidneys. It works by stimulating the production of red blood cells by the bone marrow. Epoetin alfa belongs to a group of medications known as erythropoiesis-stimulating agents (ESAs).

Effects of Epoetin Alfa

Several studies have evaluated the safety and efficacy of epoetin alfa for the treatment of anemia due to a variety of conditions. These studies evaluated the efficacy of the medications by measuring hematocrit, which is a blood test that measures how much of the blood consists of red blood cells and is a good measure of anemia.
These studies showed that epoetin alfa can increase hematocrit, indicating that it is an effective treatment for anemia. In many situations, the drug was also shown to decrease the need for blood transfusions.
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