More Medicines That React With Invirase

Invirase Interactions Explained

The following sections explain in detail the potentially serious but often manageable interactions that can occur when Invirase is combined with any of the drugs listed above.
Invirase may increase the level of bosentan in your blood. Your healthcare provider may need to lower your bosentan dosage while you are taking Invirase.
Calcium Channel Blockers
Invirase may increase the level of calcium channel blockers in your blood, possibly increasing the risk of side effects. Your healthcare provider may need to lower the dose of your calcium channel blocker to prevent this interaction from occurring.
Certain Antibiotics or Antifungals
Combining Invirase with certain antibiotics or antifungals may increase or decrease the level of both Invirase and the antibiotic or antifungal in your blood. Check with your healthcare provider before taking Invirase with any of these medications. It should never be combined with rifampin, as it can make Invirase less effective and may cause liver damage.
Certain Antipsychotics or Phenothiazines
Phenothiazine and certain antipsychotics may increase the risk of a dangerous irregular heart rhythm when combined with Invirase. Check with your healthcare provider before combining such medications.
Certain Benzodiazepines
As stated previously, Invirase should not be combined with oral midazolam or triazolam, due to the risk of life-threatening reactions. If you take Invirase with any other benzodiazepine medications, your healthcare provider may recommend a lower dose of the benzodiazepines because Invirase can increase the level of these medications in the blood.

Invirase Drug Information

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