Invirase Drug Interactions

When arrhythmia medications, calcium channel blockers, and certain antibiotics are taken with Invirase, drug interactions may occur. Some of these interactions can alter the amount of the medications in your blood, possibly increasing your risk of side effects or decreasing the effectiveness of the medications. If Invirase drug interactions are a concern, your healthcare provider may monitor you more closely and adjust your dosages as necessary.

Invirase Drug Interactions: An Overview

Invirase® (saquinavir mesylate) can potentially interact with several other medicines. Some of the possible Invirase drug interactions are extremely serious, due to the increased risk of very serious problems, such as a life-threatening irregular heart rhythm (arrhythmia). Other interactions are potentially serious but can be managed with careful monitoring.

Life-Threatening Invirase Drug Interactions

The list of medications that should never be combined with Invirase due to the possibility of extremely dangerous problems includes:
  • Cisapride (Propulsid®)
  • Ergot medications, such as:
    • Bromocriptine (Parlodel®)
    • Dihydroergotamine (Migranal®)
    • Ergonovine
    • Ergotamine (Bellamine S®, Cafergot®, Ergomar®)
    • Methylergonovine (Methergine®)
    • Pergolide (Permax®)

Invirase Drug Information

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