Isentress Drug Interactions

Atazanavir, phenobarbital, and phenytoin are among the medications that may cause interactions when taken with Isentress. Drug interactions such as these may alter the amounts of medications in the blood, possible making them less effective. However, many of these Isentress drug interactions have not been adequately studied, so you should talk to your healthcare provider before taking any medications with Isentress.

 

Isentress Drug Interactions: An Overview

Isentress™ (raltegravir) can potentially interact with several other medicines. Some of the medicines that may lead to Isentress drug interactions include:
 

More Information on Interactions With Isentress

The following sections explain in detail the potentially negative interactions that can occur when Isentress is combined with any of the drugs listed above.
 
Atazanavir
Atazanavir increases the level of Isentress in your blood. However, this interaction usually does not cause any problems. Nevertheless, check with your healthcare provider before combining these two medications.
 
Phenobarbital
Theoretically, phenobarbital may decrease the level of Isentress in your blood, making it less effective. However, this interaction has not been adequately studied, so it is difficult to predict exactly how these medications affect each other. Check with your healthcare provider before taking these medications together.
 
Phenytoin
Theoretically, phenytoin may decrease the level of Isentress in your blood, making it less effective. However, this interaction has not been adequately studied, so it is difficult to predict exactly how these medications will interact. Check with your healthcare provider before taking these medications together.
(Isentress Drug Interactions Continued: Page 2)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;