Isentress is the first medication available in a group of
HIV medications known as integrase inhibitors. These medicines work by blocking a process that the HIV virus needs in order to multiply.
Like other viruses, HIV must use a person's own cells to reproduce. Once the virus makes copies of its DNA (its genetic material), it inserts the viral DNA into the DNA of the infected human cell. As a result, it can use the human cell's own machinery to make new copies of the virus.
Isentress inhibits an enzyme called integrase. Integrase is necessary for the viral DNA to be inserted into the human DNA. By inhibiting integrase, Isentress helps to prevent the virus from making new copies of itself. It is important to remember, however, that Isentress is not a cure for HIV or
AIDS.
Isentress Uses in Children
Isentress is not approved for use in children, as it has not been adequately studied in this age group. Talk with your child's healthcare provider about the benefits and risks of using the drug in children.
On occasion, your healthcare provider may recommend Isentress for treating something other than HIV infection and AIDS. This is called an "
off-label" use. At this time, there are no universally accepted off-label Isentress uses.
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