Drug Combinations With Kaletra to Avoid

Certain Benzodiazepines
Kaletra should not be combined with triazolam or oral midazolam, due to the risk of life-threatening reactions. The injectable form of midazolam may be used with Kaletra as long as your healthcare provider carefully monitors you for increased effects of the midazolam.
 
Certain Chemotherapy Drugs
Kaletra may increase the level of certain chemotherapy drugs in the blood, increasing the risk of chemotherapy side effects. Your healthcare provider may decide that you should temporarily stop Kaletra or receive a lower dosage of chemotherapy, or that a different combination of medications would be more appropriate.
 
Colchicine
Kaletra may increase the level of colchicine in your blood. Your healthcare provider may need to lower your colchicine dosage while you are taking Kaletra.
  
Delavirdine
Delavirdine increases the level of Kaletra in your blood. Your healthcare provider may need to decrease your Kaletra dosage as a result.
 
Dexamethasone
Dexamethasone may decrease the level of Kaletra in your blood, perhaps making it less effective. Check with your healthcare provider before using these two medications together.
 
Digoxin
Combining digoxin with Kaletra may increase the risk of a certain irregular heart rhythm known as heart block. This may potentially be quite dangerous. If you take these medications together, your healthcare provider may want to monitor your heart to check for this problem.
  
Disulfiram
Kaletra oral solution (but not tablets) contains alcohol, which should not be combined with disulfiram.

Kaletra Medication Information

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