Lexiva Drug Interactions

Rifampin, pimozide, and ergot medications should never be taken with Lexiva. Drug interactions may occur when these medications are combined that could reduce the effectiveness of the drugs or lead to life-threatening side effects. Some of the other medications that may cause negative Lexiva drug interactions include delavirdine, efavirenz, tricyclic antidepressants, and hormonal contraceptives.

 

Lexiva Drug Interactions: An Overview

Lexiva® (fosamprenavir calcium) can potentially interact with several other medicines. Some of the medicines that may lead to Lexiva drug interactions include:
 
  • Arrhythmia medications
  • Certain antibiotics and antifungal medications, such as:
 
    • Ketoconazole (Nizoral®)
    • Itraconazole (Sporanox®)
    • Rifabutin (Mycobutin®)
    • Rifampin (Rifadin®)
 
  • Certain benzodiazepines, such as:
 
 
 
 
 
 
  • Ergot medications, such as:
 
    • Bromocriptine (Parlodel®)
    • Dihydroergotamine (Migranal®)
    • Ergonovine
    • Ergotamine (Bellamine S®, Cafergot®, Ergomar®)
    • Methylergonovine (Methergine®)
    • Pergolide (Permax®)
 
 
    • Cyclosporine (Gengraf®, Neoral®, Sandimmune®)
    • Sirolimus (Rapamune®)
    • Tacrolimus (Prograf®)
 
 
 
  • Methadone (Dolophine®, Methadose®)
  • Nevirapine (Viramune®)
  • Other protease inhibitors, such as:
 
 
 
 
 
 
  • Warfarin (Coumadin®, Jantoven®).
     
(Lexiva Drug Interactions Continued: Page 2)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;