AIDS Home > Dronabinol Dosage

The amount of dronabinol a person is prescribed will depend on the condition being treated, among other factors. This medication can be taken anywhere from two to six times a day; however, it is best to avoid taking a dose of dronabinol in the early-morning hours. This tends to increase the risk of side effects, so it is better to take this drug later in the day.

An Introduction to Dosing With Dronabinol

The dose of dronabinol (Marinol®) your healthcare provider recommends will vary, depending on a number of factors, including:
  • The reason you are taking dronabinol
  • Your height and weight
  • How you respond to the drug
  • Side effects you experience.
Your healthcare provider will adjust your dosage to give you the maximum benefit with the least likelihood of side effects. As is always the case, do not adjust your dose unless your healthcare provider specifically tells you to do so.

Dronabinol Dosage for AIDS-Associated Anorexia

People with AIDS often suffer from severe anorexia, or an inability to eat (this is different from anorexia nervosa, the well-known eating disorder), which results in weight loss. The standard initial dronabinol dose for appetite stimulation in people with AIDS is 2.5 mg twice daily: before lunch and before dinner.
This amount may be reduced to 2.5 mg just once daily, at dinner or bedtime, in people who experience significant side effects of dronabinol. If higher doses are needed, the amount may be gradually increased to a maximum of 10 mg twice a day.

Dronabinol Dosage for Chemotherapy-Related Nausea and Vomiting

This medication may be given one to three hours before cancer chemotherapy and then every two to four hours after chemotherapy, for a total of four to six doses a day. Your healthcare provider will recommend a specific dosage of dronabinol using your body surface area, which is usually calculated using your height and weight.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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