AIDS Home > Drug Combinations With Edurant to Avoid
Edurant Drug Interactions ExplainedThe following sections explain in detail the potentially negative reactions that can occur when Edurant is combined with any of the drugs listed above.
Antacids can decrease the absorption of Edurant in the body, causing it to be less effective. Make sure to take antacid medications at least two hours before or three hours after your dose of Edurant.
Certain Antibiotics or Antifungals
Combining Edurant with certain antibiotics or antifungals may increase the level of Edurant (and could decrease the level of some antifungals) in your blood. Check with your healthcare provider before taking Edurant with any of these medications.
Certain Seizure Medications
Edurant should never be combined with carbamazepine, oxcarbazepine, phenobarbital, or phenytoin, as these medications may significantly reduce the effectiveness of Edurant.
Edurant should never be combined with more than a single dose of dexamethasone, as it may significantly reduce the effectiveness of Edurant. A single, one-time dose of dexamethasone is acceptable.
H2 blockers can decrease the absorption of Edurant, making it less effective. If you absolutely must take an H2 blocker, take it at least 12 hours before or four hours after a dose of Edurant. With this type of a dosing schedule, using a twice-a-day H2 blocker is probably not possible.
Edurant can decrease the level of methadone in your blood, perhaps making it less effective. Your healthcare provider may need to increase your methadone dosage.
Proton Pump Inhibitors (PPIs)
Edurant should never be combined with PPIs, as these medications may significantly reduce the effectiveness of Edurant.