AIDS Home > Am I Taking Products That React With Edurant?
Other QT Prolongers
Several medications cause a change in the heart rhythm, known as QT prolongation, to varying degrees. If severe enough, this change can lead to a life-threatening arrhythmia known as torsades de pointes (TDP). Because Edurant can cause QT prolongation (especially at higher-than-recommended dosages), it should be used with caution and extra monitoring when combined with other QT-prolonging drugs.
Edurant is an NNRTI and should not be combined with other NNRTIs.
Rifabutin, Rifampin, or Rifapentine
Edurant should never be combined with rifabutin, rifampin, or rifapentine, as these medications may significantly decrease the effectiveness of Edurant.
St. John's Wort
Because St. John's wort can significantly reduce the level of Edurant in your blood, these medications should never be taken together.