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Edurant is a medication prescribed in combination with other medications to treat HIV and AIDS. It can help stop HIV from infecting healthy cells in the body, but it is not a cure for the virus. The medicine comes as a tablet and is taken once daily. Do not miss doses, as it may decrease the effectiveness of the drug. Potential side effects include depression, insomnia, and headaches.

What Is Edurant?

Edurant™ (rilpivirine) is a prescription medicine used as a treatment for HIV and AIDS. It is an oral medication that is taken just once a day. Edurant should not be used by itself; it is approved for use only in combination with other HIV medications.
 
(Click Edurant Uses for more information on this topic, including possible off-label uses.)
 

Who Makes This Medicine?

The medication is made by Janssen-Cilag S.p.A. for Tibotec Therapeutics, Division of Centocor Ortho Biotech Products, L.P.
 

How Does Edurant Work?

Edurant is a non-nucleoside reverse transcriptase inhibitor (NNRTI). Like other NNRTIs, it works by blocking a process that the HIV virus needs in order to multiply.
 
HIV (human immunodeficiency virus) is the virus that causes AIDS. Like other viruses, HIV must use a person's own cells to reproduce. However, HIV is a little different from other viruses, because it must first convert its genetic material from RNA to DNA. It is the DNA genes that allow HIV to multiply.
 
HIV converts its genetic material by using a special protein called the reverse transcriptase enzyme. To create DNA, this enzyme uses several different protein building blocks.
 
Edurant works by attaching to the reverse transcriptase enzyme, stopping it from making DNA. Without DNA, HIV cannot multiply.
 
Edurant is not a cure for HIV or AIDS. It can help stop HIV from infecting healthy cells in the body, but it does not help cells that have already been infected with the virus.
 
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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