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In studies on Kaletra and pregnancy, the medicine caused miscarriages, low fetal weight, and bone problems when it was given to pregnant rats. Since the risks of using the drug in humans are not fully known, healthcare providers should only prescribe it if the benefits to the woman outweigh the possible risks. If you are taking Kaletra and pregnancy occurs, contact your healthcare provider immediately.

Kaletra and Pregnancy: An Overview

Kaletra® (lopinavir and ritonavir) is a prescription HIV treatment. It may not be safe for use during pregnancy, although the benefits outweigh any possible risks in many cases.

Kaletra and Pregnancy Category C

The U.S. Food and Drug Administration (FDA) uses a category system to classify the possible risks to a fetus when a specific medicine is taken during pregnancy. Pregnancy Category C is given to medicines that have not been studied in pregnant humans but that do appear to cause harm to the fetus in animal studies. Also, medicines that have not been studied in any pregnant women or animals are automatically given a pregnancy Category C rating.
When given to pregnant rats, Kaletra increased the risk of miscarriages, low fetal weight, and bone problems. Limited experience in humans suggests that the benefits of using Kaletra during pregnancy outweigh any risks for many women.

Kaletra and Pregnancy: Final Thoughts

If you are pregnant or are thinking of becoming pregnant while taking Kaletra, let your healthcare provider know. He or she will consider both the benefits and risks of using the drug during pregnancy before making a recommendation in your particular situation. Be sure to seek early prenatal care, as women with HIV or AIDS need special care, both for themselves and their babies.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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