AIDS Home > Kaletra Dosage
Many factors will have an impact on the dose of Kaletra your healthcare provider recommends. These factors include how old you are, what other medications you are taking, and whether your particular HIV virus has developed resistance to any drugs. If you have fewer than three lopinavir resistance mutations, a dosage of 400 mg/100 mg twice daily (or 800 mg/200 mg) may be recommended.
The dose of Kaletra® (lopinavir and ritonavir) that your healthcare provider recommends will vary, depending on a number of factors, including:
- Your age
- Your weight (for children)
- Which drug resistance mutations your particular HIV virus has developed
- Other medical conditions you may have
- Other medications you may be currently taking.
As always, do not adjust your dose unless your healthcare provider specifically instructs you to do so.
Kaletra Dosage for Adults
The recommended dose of Kaletra for treating adults with HIV or AIDS depends on the number of lopinavir resistance mutations your particular virus has developed. If tests show that you have fewer than three different lopinavir resistance viral mutations, there are a few different Kaletra dosing options, including:
- Kaletra 400 mg/100 mg (two tablets or 5 mL of oral solution) twice daily
- Kaletra 800 mg/200 mg (four tablets or 10 mL of oral solution) once daily.
If you have three or more lopinavir resistance viral mutations, the once-daily dosing is not recommended. Therefore, the recommended dose of Kaletra for people in such situations is Kaletra 400 mg/100 mg (two tablets or 5 mL of oral solution) twice daily.
Your healthcare provider may suggest a higher dose if you are taking certain other HIV medications (see Kaletra Drug Interactions).
Once-daily Kaletra dosing is not recommended for people taking the following medications:
- Carbamazepine (Carbatrol®, Epitol®, Equetro®, Tegretol®)
- Phenobarbital (Luminal®)
- Phenytoin (Dilantin®, Phenytek®).
For people taking these medications, the twice-a-day dosage should be used.