Men who have prostate cancer may receive Megace® (megestrol acetate) to help treat hot flashes. However, this is an "off-label," or unapproved, use of the medication. Megace is a synthetic form of the hormone progesterone. It comes in the form of an oral suspension or tablets.
The approved uses of Megace include treating symptoms associated with breast cancer or endometrial cancer (cancer of the lining of the uterus). It is also licensed to help stimulate appetite and cause weight gain in people with acquired immunodeficiency syndrome (AIDS).
(Click Megace Uses to learn more about using this drug in men with prostate cancer. This article also describes other uses of Megace and explains how it works.)
Written by/reviewed by: Kristi Monson, PharmD;Arthur Schoenstadt, MD
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