AIDS Home > Drug Combinations With Reyataz to Avoid

Immune-Suppressing Medications
Reyataz may increase the level of some immune-suppressing medications in your blood. Your healthcare provider may need to decrease the dose of your immune-suppressing medication to prevent this interaction from occurring.
Irinotecan (Camptosar)
Reyataz should never be combined with irinotecan, due to the risk of dangerous irinotecan side effects.
Nevirapine (Viramune)
Nevirapine can decrease the level of Reyataz in your blood. Your healthcare provider may need to increase your Reyataz dosage or recommend a different combination of medications.
Oral Contraceptives (Birth Control Pills)
Reyataz may make oral contraceptives less effective. You should use a non-hormonal method of contraception (such as condoms) while taking Reyataz.
Other Protease Inhibitors
Taking Reyataz with another protease inhibitor may increase the level of both medications in your blood. Check with your healthcare provider before taking two protease inhibitors together. In general, Reyataz should not be combined with indinavir, due to the risk of dangerous reactions.
Phosphodiesterase Type 5 Inhibitors (PDE5 Inhibitors)
Reyataz can increase the level of PDE5 inhibitors in your blood, increasing your risk of side effects. You healthcare provider may recommend a lower-than-typical dosage for your PDE5 inhibitor while you are taking Reyataz.
At this time, it is recommended that if you take sildenafil for the purpose of treating pulmonary arterial hypertension, you should not take Reyataz, as a safe and effective dosage of sildenafil for this situation has not yet been established.
Pimozide (Orap)
Pimozide and Reyataz should not be taken together, due to the risk of dangerous reactions.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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