Selzentry is commonly prescribed to treat AIDS and HIV. It is specifically designed for a certain type of HIV (CCR5-tropic HIV), and it works by preventing the virus from entering human cells. Selzentry comes in tablet form and is typically taken twice daily. Although most people tolerate the medication well, side effects can occur and may include fever, rashes, and coughing.
What Is Selzentry?
Selzentry™ (maraviroc) is a prescription medication used as a treatment for HIV and AIDS. It should always be used in combination with other HIV medications and is only approved for treating certain types of HIV infection (not all types of the virus are susceptible to Selzentry).
Selzentry belongs to a group of HIV medications known as entry inhibitors. These medicines work by preventing the virus from entering human cells.
HIV (human immunodeficiency virus) is the virus that causes AIDS. There are different types of this virus. One type attaches to the CCR5 receptors on human cells in order to attach to and then enter the cells. This type of HIV is called CCR5-tropic HIV. There are other types of HIV that bind to other receptors. Selzentry binds to the CCR5 receptor, preventing HIV from binding to and entering human cells. The drug is effective only for treating the CCR5-tropic HIV type; it does not work for the other types of HIV.
Written by/reviewed by: Kristi Monson, PharmD;Arthur Schoenstadt, MD
Last reviewed by: KristiMonson, PharmD;
List of references (click here):
Selzentry [package insert]. Research Triangle Park, NC: ViiV Healthcare;2011 July.
Food and Drug Administration, Center for Drug Evaluation and Research. Electronic orange book: Approved drug products with therapeutic equivalence evaluations. FDA Web site. Available at: http://www.fda.gov/cder/ob/. Accessed October 17, 2007.
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