AIDS Home > Truvada Side Effects
In clinical studies, nausea, dizziness, diarrhea, and fatigue were the most commonly reported Truvada side effects. In most cases, side effects are minor and easily treated. However, you should seek medical attention immediately if you develop any serious side effects of Truvada, such as high cholesterol or triglycerides, kidney problems, changes in body fat distribution, or allergic reactions.
As with any medicine, side effects are possible with Truvada® (emtricitabine and tenofovir disoproxil fumarate); however, not everyone who takes the drug will experience side effects. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or can easily be treated by you or your healthcare provider.
(This article covers many, but not all, of the possible side effects with Truvada. Your healthcare provider can discuss a more complete list of Truvada side effects with you.)
Clinical studies have not evaluated Truvada alone for the treatment of HIV, since it is meant to be used along with other HIV medications. In fact, the available information on side effects involves studies that used Truvada plus another HIV medication. Therefore, it is difficult to determine whether these side effects are actually due to Truvada or the other HIV medications.
In these studies, the most common side effects of Truvada (plus another HIV medication) included:
- Dizziness -- in up to 8 percent of people
- Nausea -- up to 8 percent
- Diarrhea -- up to 7 percent
- Fatigue -- up to 7 percent
- Headaches -- up to 5 percent.
Other common side effects (occurring in 1 to 4 percent of people) included: