Megace Elderly

Megace® (megestrol acetate) is a medicine approved to stimulate appetite and cause weight gain in people with acquired immunodeficiency syndrome (AIDS). It is also approved to help relieve symptoms caused by breast cancer or endometrial cancer (cancer of the lining of the uterus). It is approved for use in adults only. But can elderly people use Megace?
Megace has not been adequately studied in older adults to determine if they respond differently to the medication. However, because older adults may be more sensitive to the side effects, they may need to be started on lower doses. Also, older adults may have impaired kidney function, which increases the risk for Megace side effects.
(Click Megace Uses for more details on the uses for this drug. This resource discusses approved and unapproved uses. It also explains how Megace works and why it is not approved for use in children.)
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