Megace Overdose

If someone takes too much Megace (megestrol), it may cause problems, such as chest pain, high blood sugar levels, and problems walking. Make sure to seek immediate medical treatment if you believe you have overdosed on Megace. A healthcare provider may treat you by administering certain medications, pumping the stomach, and providing supportive care.

Can You Take Too Much Megace?

Megace® (megestrol acetate) is a prescription medication used to stimulate appetite in people with acquired immunodeficiency syndrome (AIDS) and to help relieve symptoms of breast cancer and cancer of the uterine lining (endometrial cancer). It belongs to a group of medicines known as progestins. As with most drugs, it is possible to overdose on Megace.
 
The specific effects of an overdose would likely vary, however, depending on a number of factors, including the Megace dosage and whether it was taken with any other medications or substances.
 

Effects of an Overdose

Doses of Megace as high as 1600 mg a day have been given without serious side effects. However, some of the reported effects of an overdose have included:
 
  • Diarrhea
  • Nausea
  • Abdominal (stomach) pain
  • Shortness of breath
  • Cough
  • Unsteady gait (problems walking)
  • Low energy
  • Chest pain
  • Increased blood pressure
  • Increased appetite
  • High blood sugar (hyperglycemia)
  • Edema (swelling), usually of the legs, ankles, and feet.
 

Treatment Options for a Megace Overdose

Treatment for an overdose of Megace may vary. If the overdose was recent, a healthcare provider may administer activated charcoal or "pump the stomach" to help reduce the amount of the medication absorbed into the bloodstream. Dialysis is not expected to be helpful for removing this medicine from the body.
 
Treatment will also involve supportive care, which consists of treating the symptoms that occur as a result of the overdose. For instance, fluids may be given through a line into a vein (intravenous, or IV, fluids) if diarrhea or vomiting causes dehydration.
 
It is important that you seek medical attention immediately if you believe that you or someone else may have taken too much Megace.
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