More Medications That Interfere With Norvir

Combining meperidine with Norvir may increase the risk of dangerous meperidine side effects. Ask your healthcare provider before taking these medications together.
Norvir may decrease the level of methadone in your blood, perhaps making it less effective or even causing methadone withdrawal symptoms. Your healthcare provider may need to increase your methadone dosage to prevent this.
Norvir may increase the level of methamphetamine in your blood, possibly increasing the risk of dangerous side effects. Norvir should not be combined with street versions (illegal versions) of methamphetamine. If you are taking the prescription version of methamphetamine, your healthcare provider may need to decrease your dosage.
Both Norvir capsules and oral solution contain alcohol. It is not a good idea to take Norvir and metronidazole together, as dangerous side effects may occur due to the alcohol in Norvir.
Other Protease Inhibitors
Norvir usually increases the level of other protease inhibitors in the blood. In fact, this is usually used as a beneficial drug interaction in order to make other protease inhibitors more effective.
Phosphodiesterase Type 5 Inhibitors (PDE5 Inhibitors)
Norvir can increase the level of PDE5 inhibitors in your blood, increasing your risk of side effects. Your healthcare provider may recommend a lower-than-typical dosage for your PDE5 inhibitor while you are taking Norvir.
PDE5 inhibitors are used to treat erectile dysfunction or pulmonary arterial hypertension. Specific dosing recommendations are available for combining Norvir with a PDE5 inhibitor if the PDE5 inhibitor is used to treat erectile dysfunction. Also, specific dosing recommendations are available for combining Norvir with tadalafil when tadalafil is used to treat pulmonary arterial hypertension.
However, at this time it is not recommended to combine Norvir with sildenafil when sildenafil is used to treat pulmonary arterial hypertension, as a safe and effective dosing regimen has not yet been determined for this situation.
Pimozide and Norvir should not be taken together, due to the risk of dangerous reactions.

Norvir for HIV/AIDS

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