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from eMedTV.comSelenium Interactions Explained
The following sections explain in detail the potentially negative interactions that can occur when selenium is combined with any of the drugs listed above.
Anticoagulant or Antiplatelet Medications
Theoretically, combining selenium with anticoagulant or antiplatelet medications could increase the risk of bleeding. However, the significance of this interaction is not yet known. If you take an anticoagulant or antiplatelet medication, do not take selenium supplements without your healthcare provider's approval and supervision.
Barbiturates
Selenium could delay the breakdown of barbiturates in the body, causing a prolongation of sedation or other barbiturate effects. Check with your healthcare provider before combining selenium with a barbiturate.
Niacin
One study has suggested that selenium (in combination with vitamin C, vitamin E, and beta-carotene) may decrease the effectiveness of niacin. However, more research is necessary to confirm this interaction.
Statins
One study has suggested that selenium (in combination with vitamin C, vitamin E, and beta-carotene) may decrease the effectiveness of statin medications. However, more research is necessary to confirm this interaction.
Final Thoughts on Selenium Drug Interactions
It is possible that not every drug interaction was discussed in this article. In fact, early research suggests that selenium may inhibit the liver enzymes from breaking down many different medications, causing higher levels of such drugs to accumulate in the body. Therefore, you should talk with your pharmacist or healthcare provider about the selenium drug interactions that may apply to you.
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD