Sustiva and Pregnancy

In clinical studies on Sustiva and pregnancy, the medication caused serious birth defects when it was given to pregnant monkeys. Some studies also suggest that the drug may increase the risk of birth defects in humans. Due to these potential complications, Sustiva is generally not recommended for pregnant women. If you are taking Sustiva and pregnancy occurs, notify your healthcare provider immediately.

 

Sustiva and Pregnancy: An Overview

Sustiva® (efavirenz) is a prescription HIV treatment. Based on problems in animal studies and reports of problems in humans, Sustiva may not be safe for use during pregnancy.
 

Sustiva and Pregnancy Category D

The U.S. Food and Drug Administration (FDA) uses a category system to classify the possible risks to a fetus when a specific medicine is taken during pregnancy. Pregnancy Category D is a classification given to medicines that have been shown to present a risk to the fetus in studies of pregnant women but may still offer benefits that outweigh the risks. A pregnancy Category D medicine may still be given to a pregnant woman if the healthcare provider believes that the benefits to the woman outweigh the possible risks to the unborn child.
 
Giving Sustiva to pregnant monkeys increased the risk of serious birth defects. Studies in humans have also suggested an increased risk of birth defects, although more thorough studies are needed before the full risks are known.
 

Sustiva and Pregnancy: Final Thoughts

If you are pregnant or are thinking of becoming pregnant while taking Sustiva, let your healthcare provider know. He or she will consider the benefits and risks of taking Sustiva during pregnancy before making a recommendation in your particular situation. Be sure to seek early prenatal care, as women with HIV or AIDS need special care -- both for themselves and their babies.
 
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;