Trizivir Drug Interactions (Cont.)

Trizivir Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when Trizivir is combined with any of the drugs listed above.
 
Alcohol
Drinking alcoholic beverages can increase the level of abacavir (one of the components of Trizivir) in your blood, perhaps increasing your risk of side effects. It may be a good idea to avoid alcohol while taking Trizivir.
 
Atovaquone (Mepron)
Taking atovaquone with Trizivir may increase the level of Trizivir in your blood, increasing your risk of Trizivir side effects. Talk with your healthcare provider before taking these medications together.
 
Doxorubicin (Adriamycin, Doxil, Evacet)
Doxorubicin can make Trizivir less effective and may also increase the risk of Trizivir side effects. In general, these medications should not be taken together.
 
Fluconazole (Diflucan)
Fluconazole may increase the level of Trizivir in your blood, increasing your risk of side effects. Talk with your healthcare provider before using these medications. You may need to be monitored more closely.
 
Ganciclovir (Cytovene)
Combining ganciclovir with Trizivir may increase your risk of Trizivir side effects, particularly side effects that affect blood cells. Your healthcare provider may need to monitor your blood counts very closely.
 
Interferon Medications
Combining an interferon with Trizivir may increase your risk of Trizivir side effects, particularly side effects that affect blood cells. Your healthcare provider may need to monitor your blood counts very closely.
 
Methadone (Dolophine, Methadose)
Methadone may increase the level of Trizivir in your blood, increasing your risk of side effects. Also, it is possible that Trizivir may decrease the level of methadone in your blood, making it less effective. Talk with your healthcare provider before taking these medications together.
(Trizivir Drug Interactions Continued: Page 3)

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;