Trizivir Drug Interactions

Doxorubicin, ribavirin, and stavudine are medications that should generally not be taken together with Trizivir. Drug interactions may also occur if Trizivir is combined with fluconazole, methadone, or ribavirin. These interactions can increase your risk of serious side effects or reduce the effectiveness of the medicines. Since many drugs could cause Trizivir interactions, talk to your healthcare provider before taking any other medications.

 

Trizivir Drug Interactions: An Introduction

Trizivir® (abacavir/lamivudine/zidovudine) can potentially interact with several other medicines. Some of these medicines that may lead to Trizivir interactions include:
 
  • Alcohol
  • Atovaquone (Mepron®)
  • Doxorubicin (Adriamycin®, Doxil®, Evacet™)
  • Fluconazole (Diflucan®)
  • Ganciclovir (Cytovene®)
  • Interferon medications, such as:

 

    • Interferon alfa-2a (Roferon®-A)
    • Interferon alfa-2b (Intron® A)
    • Interferon alfa-2b and ribavirin (Rebetron®)
    • Interferon alfa-n3 (Alferon® N)
    • Interferon alfacon-1 (Infergen®)
    • Interferon beta-1a (Avonex®, Rebif®)
    • Interferon beta-1b (Betaseron®)
    • Interferon gamma-1b (Actimmune®)
    • Peginterferon alfa-2a (Pegasys®)
    • Peginterferon alfa-2b (Pegintron™)

 

(Trizivir Drug Interactions Continued: Page 2)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;