Viramune Uses (Cont.)

How Does Viramune Work?

Viramune belongs to a group of HIV medications known as non-nucleoside reverse transcriptase inhibitors (NNRTIs). These medicines work by blocking a process that the HIV virus needs in order to multiply.
 
HIV (human immunodeficiency virus) is the virus that causes AIDS. Like other viruses, HIV must use a person's own cells to reproduce. However, HIV is a little different from other viruses because it must first convert its genetic material from RNA to DNA. It is the DNA genes that allow HIV to multiply.
 
HIV converts its genetic material by using a special protein called the reverse transcriptase enzyme. To create DNA, this enzyme uses several different protein building blocks.
 
Viramune works by attaching to the reverse transcriptase enzyme, stopping it from making DNA. Without DNA, HIV cannot multiply. Viramune is not a cure for HIV or AIDS. It can help stop HIV from infecting uninfected cells in the body, but it does not help cells that have already been infected with the virus.
 

Viramune Use in Children

Viramune is approved for use in children as young as 15 days old. Talk with your child's healthcare provider about the benefits and risks of using Viramune in children.
 

Off-Label Viramune Uses

On occasion, your healthcare provider may recommend Viramune for treating something other than HIV infection and AIDS. This is called an "off-label" use. At this time, Viramune is used off-label to prevent HIV infection in people exposed to the HIV virus (such as a healthcare worker who comes in contact with a contaminated needle stick). This is called postexposure prophylaxis (PEP).
 

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;