More Info on Zerit Indications

How Does Zerit Work?

Zerit is part of a group of medications known as nucleoside reverse transcriptase inhibitors (NRTIs). NRTI medications work by blocking a process that the HIV virus needs in order to multiply.
 
HIV (the human immunodeficiency virus) is the virus that is responsible for AIDS. Like other viruses, HIV must use a person's own cells to reproduce. However, HIV is different than other viruses because it must first convert its genetic material from RNA to DNA. It is the DNA genes that allow HIV to multiply.
 
HIV converts its genetic material into DNA by using a special protein called the reverse transcriptase enzyme. To create DNA, this enzyme uses several different molecular building blocks.
 
Zerit works by tricking reverse transcriptase into thinking it is one of these molecular building blocks. However, it is just different enough that when used to create DNA, Zerit actually stops the DNA from being made. Without DNA, HIV cannot multiply.
 
Zerit is not a cure for HIV or AIDS. Although it can help stop HIV from infecting uninfected cells in the body, it does not help cells that have already been infected with the virus.
 

Zerit Use in Children

Zerit is approved for use in children, including newborns. Talk with your child's healthcare provider about the benefits and risks of using Zerit in children.
 

Off-Label Zerit Uses

On occasion, your healthcare provider may recommend Zerit for treating something other than HIV infection and AIDS. This is called an "off-label" use. At this time, Zerit is used off-label to prevent HIV infection in people exposed to the HIV virus (such as a healthcare worker who is stuck with a contaminated needle). This is called postexposure prophylaxis (PEP).

Zerit Drug Information

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